The Greb Group

Research

The Greb Research Group explores the influence of strong ligand effects on the reactivity and physicochemical properties of p-block elements to expand the usual reactivity and property profiles of the Earth's most common elements. By dramatically altering the electronic structure through structural constraint or enabling element-ligand cooperativity, new reaction pathways for activating small molecules are discovered. Subtle changes in the oxidation states of p-block elements are achieved by interplay with redox-active ligands (Electromerism). Further, the group pursues a systematic study of the concept of Lewis acidity using data-driven methods. State-of-the-art computational approaches parallel all synthetic projects conducted in our group.

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Recently Published
N. F. Baier, P. Cieslik, H. Rudolf, M. Pretze, B. Wängler, R. Schirrmacher, L. Greb, G. Fricker, Z. Varga, A. Kovács, C. Wängler:
Macropa Scaffold Expansion for Actinium-225 Chelation: A Synthetic Strategy, Labeling Kinetics, and Theoretical Calculations
Inorg. Chem. 2026, Accepted Manuscript.
L. Stoess, J. A. Davis, L. Greb:
Photoswitching Lewis Acid Catalysis with Highly Fatigue Resistant Photochromic Boronates
J. Am. Chem. Soc. 2026, 148, 7, 7951–7960.
Openings

Internship, Bachelor, Master, PhD, and PostDoc applicants are welcome to contact Lutz Greb.